How Big Meat Distorted the Evidence

How Big Meat Distorted the Evidence

Big Meat downplays the magnitude of meat mortality. A series of studies published in the Annals of Internal Medicine found a statistically significant association between lower consumption of red and processed meats and lower total mortality (meaning living a longer...
How Much Do New Chemotherapy Drugs Extend Life?

How Much Do New Chemotherapy Drugs Extend Life?

If you put together all the new chemotherapy drugs approved over a dozen years, the average overall survival benefit is only 2.1 months. Though we often hear new cancer drugs described as “game changers” or “breakthroughs,” most afford much more modest benefits. In my...
Chemotherapy Is Expensive—Is It Effective?

Chemotherapy Is Expensive—Is It Effective?

Most chemotherapy drugs are approved by the U.S. Food and Drug Administration (FDA) without evidence that they benefit survival or quality of life. By 2030, the number of new cancer cases in the United States is expected to skyrocket by 45%, from 1.6 million to 2.3...
Does Less Protein Increase FGF21 for Longevity?

Does Less Protein Increase FGF21 for Longevity?

Fasting and exercise can boost the longevity hormone FGF21, but what can we eat—or avoid eating—to get similar effects? Over a century ago, fasting was hailed not only as a means of combating “cerebral lassitude,” but also for the “prolongation of healthy longevity.”...
How to Boost Your Longevity Hormone

How to Boost Your Longevity Hormone

What can we do to boost the longevity hormone FGF21? In the year 2000, a new human hormone was discovered. It was the 21st documented fibroblast growth factor, so they called it FGF21. Since its discovery, FGF21 has become recognized as a key agent for the promotion...
How Prebiotic Foods Keep Your Microbiome Healthy

How Prebiotic Foods Keep Your Microbiome Healthy

We co-evolved a symbiosis with our good gut bacteria, but we aren’t holding up our end of the bargain. If you look at the classics—the most frequently cited articles in the scientific nutrition literature—the original glycemic index paper ranks tenth, cited more than...